Emit enables discovery by bridging the gap between in vivo imaging and pathology. Our technology uniquely enables high resolution imaging combined with a whole body comprehensive 3D data set. This technology can dramatically increase the value of each sample in a multi modal study. The Emit Imaging system is a high throughput whole organ/body sectioning and imaging system which produces a 3D fluorescence and corresponding anatomical data set. Powerful reconstruction and analysis tools are then used to report levels and location of target fluorescence throughout the tissue.